Come to think of how we got to the

present situation of global high inflation,

we come to realize earnestly that we are

experiencing a special moment in history;

a moment in which humanity is under

threat from a host of factors. Just call to

mind, the immense threat from climate

change, the COVID 19 pandemic and

now, the increasing Global geopoliti-

cal tensions. All these threats persist and

proliferate despite unceasing alarm of

catastrophic consequences by experts

and by a plethora of unpleasant

experiences.

In point of fact, the present situation of

high inflation is just one of such alarms;

just one unpleasant experience from the

austere threats of our time; just one but

one with evolving revolving ramifica-

tions pestering every essential pillar of

our livelihood.

Come to think of it, inflation is pestering

our labour market – discouraging

investors and investment, then contri-

buting to higher unemployment as we

have it today. Inflation is pestering the

purchasing value of money – weakening

and even eroding our food security,

healthcare security systems. Today,

while the cost of essential food items to

prepare meals continues to increase due

Director’s message

High inflation translates into

increased distress for all but

especially for the afflicted like

cancer patients and cancer

survivors

FWHPWI’s Events

FWHPWI first survey work

has been published as book

chapter

Research News

Major clinical research advances in

gynecologic cancer in 2021

Researchers weigh Obesity and

gynecological cancers relationship

Studies focus the effects of gynec-

ological cancer and its treatment

on bone mineral density

More Evidence That Alcohol Is

Contributing to a Rise in Cancer

Researchers discover genes that

predict good response to blood

cancer therapy

An experimental cancer drug had

a 100% success rate

Palmitic acid not only contribute

to metastasis, but also exerts long-

term effects on the genome

The Tissue surrounding breast

cancer tumours can prevent im-

mune cells from reaching and

destroying cancer cells

A study analyses prevalence use of

medicinal plants by cancer patients

Scientists have found out that Soft

Sea Corals are sources of sought–

after “Anti-Cancer” compound

Researchers have found a plant

compound to be effective at stopp-

ing the growth of lung cancer cells

in a laboratory setting

Cancer News: Africa

Where does cancer care stand in

Africa today?

In Kenya researchers find eviden-

ce that a single dose of HPV vacc-

ine can protect against cancer

causing infections

Africa lacks sufficient health care

resources and infrastructure to

handle the growing cancer burden

A study has been conducted to

identifying the most promising

cancer prevention and treatment

approaches available in Africa

Health and lifestyle

World Cancer Research Fund

International (WCRF) recommends

limiting ‘fast foods’ and other

processed foods high in fat,

starches or sugars

Recipe for Vegan Banana

Cinnamon Vanilla Shake

July, 2022

FWHPWI

Foundation for Women’s Health Promotion and Welfare Initiatives

In this Issue:

Dr. F. N. Alaribe Nnadozie,

(MD, FWHPWI)

DIRECTOR’S MESSAGE: High inflation translates into increased distress for all but

especially for the afflicted like cancer patients and cancer survivors

healthcare systems, values of our

pensions, savings, treasures, etc.

Today, while the cost of essential food

items to prepare meals continues to

increase due to what economists

describe as, disrupted harvests, disru-

pted supply chain, etc., the unfortunate

reality of COVID 19 pandemic and

geopolitical issues exacerbate many

other factors that lead to food

insecurity, like unemployment or red-

uced hours at work, fuel hike, and

economic sanctions. Sure, a great pro-

portion of humanity is feeling the heat,

but there are some who are closer to

harsher temperatures.

Our thought goes to people who are hit

harder, especially people who are

facing food insecurity due to the

trending inflation but highly vulnerable

because afflicted by some harsh

disease. Doubtlessly, in this itchy time,

it is tougher to struggle for employ-

ment, food, medication, and other

essential livelihood factors; but it is

much tougher to struggle for very

special or prescribed diet, prescribed

medication, prescribed lifestyle, all

under the general increased cost of

living – transportation to medical

centres and facilities, medical ticket or

fee-for-service, etc. In a nutshell,

excessive inflation is bad for all but

remarkably bad for the afflicted.

FWHPWI urges everyone in every

society to help advocate against

inflation in medicine and medication.

Perhaps it is time to try to restructure

our health care systems, abolishing or at

least replacing the fee-for-service

structure with something better for

everyone in every society.

Page 1

FWHPWI’s outreach/meeting is back

face to face. Thanks to all, over the past

two years we have had very memorable

virtual interactive experience despite all

odds of the COVID 19 pandemic.

Henceforth, following the government’s

relaxation of COVID 19 social restric-

tion rules, our coming outreach/meetings

will take place normal at designated

venues. However, should the need arise,

we shall reverse the relaxations and

implement relevant regulations and

protocols stipulated by competent

health/public authorities.

Our next outreach/meeting is scheduled

for July 30; time and venue will be

communicated. We look forward to

embracing you all.

The Editorial Group of FWHPWI is glad

to present to you our first survey-work,

published as book chapter, in S. Kumar

(ed.), Medicinal Plants, IntechOpen

London. You can click on the link below

to access the book. Happy reading.

https://www.intechopen.com/online-

first/81650.

e taking place

n desi

members and scheduled January 30, 2021

meeting and outreach was promptly held. Dr

Sylvia Kama-kieghe (UK based General

Practitioner, founder and Lead Clinician of

AskAwayHealth.Org) was the guest speaker.

Dr Kama-kieghe’s awareness talk was on

‘COVID-19 Vaccine’. She highlighted

challenges of coming into terms with the impact

of a pandemic disease; and lucidly explained

facts of vaccine hesitancy and scepticism. Dr.

Kama-Kieghe provided clarity on some

questions regularly asked by the public, such as:

Is COVID-19 vaccine bigger threat than the

disease? Does the vaccine transform human

DNA? Who should have the vaccine? Etc.

Dr Kama-kieghe’s talk also provided clarity on

‘types of COVID-19 vaccine present at the

moment’, their content, manufacturers, how the

vaccines work and some common observed side

Major clinical research advances in

gynecologic cancer in 2021

The Journal of Gynecologic Oncology

review group has held a conference and

compiled a list of major clinical studies

on gynecologic cancer since 2020. With

support from the Asian Society of

Gynecologic Oncology (ASGO), a

review course titled, “Major Clinical

Advances in Gynecologic Cancer” was

held at Daeyang AI Center at Sejong

University on December 11, 2021.

Researchers weigh Obesity and gyne-

cological cancers relationship

Obesity impacts cancer hallmarks

through different mechanisms. In gyne-

cological cancers, this occurs mainly

through alterations in hormonal,

inflammatory, and metabolic

pathways.

Increased estrogen

signaling, obesity-related insulin

through alterations in hormonal, inflamm-

atory, and metabolic pathways. Increas-

ed estrogen signaling, obesity-related

insulin resistance, and chronic low-grade

inflammation contribute in concert to

stimulate anabolic processes, inhibit

apoptosis, and stimulate cell prolifera-

tion, in part, by altering the mitogenic

PI3K/AKT/mTOR pathway. Additionally,

obesity leads to major alterations in the

lipidic composition of organelles and

membrane dynamics which may further

contribute to the alteration of cancer

hallmarks.

Studies focus the effects of gyneco-

logical cancer and its treatment on

bone mineral density

In the present study, ovarian cancer

patients had a lower BMD in the 1st to

4th lumbar spine and a lower average T

score of L1–L4 than those of the control

group before treatment. More than half

(57.3%) of the ovarian cancer patients

were in advanced stages of the disease.

The long period of exposure to estrogen

deprivation due to ovarian failure

presumably influenced the low BMD

before treatment.

More Evidence That Alcohol Is

Contributing to a Rise in Cancer

Studies discover new evidence linking

alcohol consumption with increased

cancer risk. The evidence comes as

researchers assessed estimated global

alcohol consumption, risks of alcohol for

specific cancer types, and global

incidence of those cancers in 2020.

Findings showed that drinking contribu-

ted to 741,300 cases of newly diagnosed

esophageal, mouth, larynx,

FWHPWI’S EVENTS

HPV

OVERVIEW/SYMPTOMS

HPV is the most common

sexually transmitted infection.

Many people with HPV

don't develop any symptom

but can still infect others

through sexual contact.

Symptoms may include

warts on the genitals or sur-

rounding skin.

There's no cure for the virus

and warts may go away on

their own. Treatment focu-

ses on removing the warts.

A vaccine that prevents the

HPV strains most likely to

cause genital warts and

cervical cancer is recomm-

ended for boys and girls.

RESEARCH NEWS

Cancer is a leading

cause of premature

death in every

country in the world

But many of these

deaths can be

prevented

Click to join us

share information about the cancers

Almost all

cervical cancer

is caused by HPV

Some cancers of the penis, anus,

and oropharynx

(back of the throat, including the

base of the tongue and tonsils)

are also caused by HPV.

Page 2

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for our

previous newsletters/free

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of our Newsletter

esophageal, mouth, larynx, colon,

rectum, liver, and breast cancer.

Moderate drinking (<.70 ounces per day)

contributed to nearly 14 percent

(103,100) of cases, while risky drinking

(.70 to 2.11 ounces per day) contributed

to about 39 percent (29,800) of cases,

and heavy drinking (>2.11 ounces per

day) contributed to about 48 percent

(227,900) of cases.

Researchers discover genes that pre-

dict good response to blood cancer

therapy

Mount Sinai scientists sequenced RNA

of multiple myeloma tumours from

patients treated with selinexor and

identified a signature of three genes that

were activated in patients who had

positive responses. Selinexor is part of

many groundbreaking therapies for the

blood cancer multiple myeloma, but the

ability to target its use to patients who

would benefit the most remained elusive

until now.

An experimental cancer drug had a

100% success rate

A tiny group of people with rectal cancer

just experienced something of a

scientific miracle; their cancer simply

vanished after an experimental treat-

ment. This was result of a very small

trial done by doctors at New York's

Memorial Sloan Kettering Cancer

Center. Patients took a drug called

dostarlimab for six months. The trial

resulted in every single one of their

tumors disappearing. The trial group

included just 18 people, and there's still

more to be learned about how the

treatment worked. But some scientists

say these kinds of results have never

been seen in the history of cancer

research.

Palmitic acid not only contribute to

metastasis, but also exerts long-term

effects on the genom.

Metastasis – or the spread – of cancer

remains the main cause of death in

cancer patients and the vast majority of

people with metastatic cancer can only

Palmitic acid not only contribute to

metastasis, but also exerts long-term

effects on the genome

Metastasis – or the spread – of cancer

remains the main cause of death in

cancer patients and the vast majority of

people with metastatic cancer can only

be treated, but not cured. Scientists in

Spain have uncovered how a fat

molecule found in palm oil, called

palmitic acid, alters the cancer genome

and increases the likelihood cancer will

spread. The researchers have started

developing therapies that interrupt this

process and say a clinical trial could start

in the next couple of years.

The Tissue surrounding breast cancer

tumours can prevent immune cells

from reaching and destroying cancer

cells

In recent years, immunotherapy has

become an important weapon in the

arsenal against breast cancer, but many

patients still fail to respond to the

treatment. Scientists have now found

that the reason so many patients don’t

respond might not be the tumor itself but

the tissue that surrounds it – the

extracellular matrix.

A study analyses prevalence use of

medicinal plants by cancer patients

The use of medicinal plants has

increased significantly in recent years.

According to World Health Organization,

80% of the world's population uses

medicinal plants to treat themselves.

Hence, at the National Institute of

Oncology, Rabat, a cross-sectional survey

has be conducted aiming to estimate the

prevalence of medicinal plant use by

cancer patients, list the different plants

and identify their adverse effects cited

by users and their reported efficacy.

A study analyses prevalence use of

medicinal plants by cancer patients

The use of medicinal plants has

increased significantly in recent years.

According to World Health Organization,

80% of the world's population uses

medicinal plants to treat themselves.

Hence, at the National Institute of

Oncology, Rabat, a cross-sectional survey

has been conducted aiming to estimate

the prevalence of medicinal plant use by

cancer patients, list the different plants

and identify their adverse effects cited

by users and their reported efficacy.

Just a few ways to

reduce your risk of

gynecological cancers

advised by

National Foundation

for Cancer Research

Have your Pap test

by age 21

The Pap test looks for abnormal

cell changes in the cervix to

detect cervical cancer in its early

stages.

Protect yourself from

Human papilloma

virus (HPV)

Talk to your doctor about

getting the HPV test and HPV

vaccine. Also, limit your sexual

partners and, when you do have

sex, use a condom.

Don’t smoke.

Smoking increases the risk of

different cancers including

cervical, ovarian, vaginal and

vulvar cancers.

Make healthy

choices.

It’s important to maintain a

healthy weight, be active and eat

a healthy diet consisting of fruit,

vegetables, lean proteins and

whole grains.

Share your family

history with your

doctor.

Genetic testing is now available

to see if you carry a BRCA1 or

BRCA2 mutation, which could

put you in a high-risk category

for ovarian and breast cancer. If

you carry a genetic mutation

associated to Lynch Syndrome,

a heredity condition that

increases your risk of colon

cancer, ovarian cancer, uterine

cancer, etc.

Contact your doctor

if you notice any of

these symptoms.

Abnormal vaginal

bleeding or discharge

Pelvic pain or

pressure

Abdominal or back

pain

Bloating

Changes in bathroom

habits (increased

urination, constipation,

diarrhea)

Itching or burning of

the vulva

Changes in vulva

color or skin (rash,

sores, warts, ulcers).

nfcr.org/

Page 3

Scientists have found out that Soft Sea

Corals are sources of sought–after

“Anti-Cancer” compound

For 25 years, drug hunters have been

searching for the source of a natural

chemical that had shown promise in

initial studies for treating

cancer. Now, researchers at University

of Utah Health report that easy-to-find

soft corals – flexible corals that

resemble underwater plants – make the

elusive compound.

Researchers have found a plant

compound to be effective at stopping

the growth of lung cancer cells in a

laboratory setting

While there is currently no cure for lung

cancer, scientists are working on

treatment options. Some of these

scientists are at the University of

Technology Sydney (UTS), where a new

study found a natural herbal compound

called berberine stops the growth of lung

cancer cells in a laboratory setting.

Berberine is a naturally-occurring plant

compound used in traditional Chinese

medicine for thousands of years. It can

be found in a variety of plants, including

barberry, goldenseal, Oregon grape, and

tree turmeric.

study found a natural herbal compound

called berberine stops the growth of lung

cancer cells in a laboratory setting.

Berberine is a naturally-occurring plant

compound used in traditional Chinese

medicine for thousands of years. It can

be found in a variety of plants, including

barberry, goldenseal, Oregon grape, and

tree turmeric.

For 25 years, drug hunters have been

searching for the source of a natural

chemical that had shown promise in

initial studies for treating cancer.

Now, researchers at University of

Utah report that easy-to-find soft

corals –

flexible corals that resemble

underwater plants – make the elusive

compound.

Soft sea corals

Image credit: healthcare.utah.edu/publicaffairs/news/2022/05/coral -anti-cancer –drug

Goldenseal

Image Credit:

https://www.wikiwand.com/en/Goldens

eal

(1) Barberry

Image Credit: bio.brandeis.edu/fieldbio/

(2) Goldenseal

Image Credit: wikiwand.com/en/Goldensea

(3) Oregon Grape

Image Credit: eatdrinkbreathe.com/oregon-

(3)

(1)

(2)

Page 4

initial studies for treating

cancer. Now, researchers

at University of Utah

report that easy-to-find

soft corals – flexible

corals that resemble under-

water plants – make the

elusive compound.

The cancer burden is

expected to nearly

double in sub-Saharan

Africa during the next

20 years as a result of

population growth and

ageing, reaching 1.5

million new cases and

1 million deaths

by 2040.

To overcome this

mounting challenge,

each country in sub-

Saharan Africa needs

to implement a cancer

control programme as

part of national health

planning and to have

at its disposal routine

surveillance systems

capable of monitoring

progress in the

delivery of specific

interventions.

IARC/WHO PRESS

RELEASE

10 May 2022

The COVID-19

pandemic is not over.

Never

forget this practice!

It is necessary

for your health

now and always.

Do it often.

The best for you is to

keep safe for yourself

and for us all.

Where does cancer care stand in

Africa today?

According to Dr Miriam Mutebi, the

new President, African Organization for

Research and training in Cancer, cancer

care has improved significantly in many

African countries over the past decade

but challenges in prevention, detection

and treatment services as well as

financial hurdles are limiting access to

quality and adequate care to millions of

patients.

In Kenya researchers find evidence

that a single dose of HPV vaccine can

protect against cancer causing

infections.

A recent study in Kenya renews

optimism in the efficacy of human

papillomavirus (HPV) vaccine. The

study adds to growing evidence that a

single dose of HPV vaccine is highly

effective in protecting young women

against cervical infection with cancer-

causing HPV types. Conceivably, the

exciting aspect of the study is the reality

that giving just one HPV vaccine dose

instead of the two or three doses

currently recommended would reduce

the cost of vaccination, hence allowing

more girls worldwide to be vaccinated.

Africa lacks sufficient health care

resources and infrastructure to handle

the growing cancer burden

Researchers estimate that there will be

2.1 million new cancer cases and 1.4

million cancer-related deaths in Africa

by 2040. The investigators noted that

dietary and lifestyle changes, along with

behavioral and environmental risk factors

may be contributing to the increase. The

findings shed light on critical needs and

could help with allocating resources. The

researchers warn that unless steps are

taken to increase awareness, improve

prevention and mitigate risk factors,

these increases would likely overwhelm

health care capacity levels, delay cancer

screenings and limit treatment options

for patients.

healthcare capacity levels, delay cancer

screenings and limit treatment options

for patients.

A study has been conducted to identify

the most promising cancer prevention

and treatment approaches available in

Africa

To do this, researchers collected and

analysed the incidence and fatality rates

for the 10 most common and fatal

cancers in 56 African countries grouped

into 5 different regions (North, West,

East, Central and South) over 16-years

(2002–2018). They examined temporal

and regional trends by investigating the

most important risk factors associated to

each cancer type. Data were analysed by

cancer type, African region, gender,

measures of socioeconomic status and

the availability of medical devices.

World Cancer Research Fund

International (WCRF) recommends

limiting ‘fast foods’ and other process-

ed foods high in fat, starches or sugars,

as this helps control calorie intake and

maintain a healthy weight

According to WCRF, there is strong

evidence that diets containing greater

amounts of ‘fast foods’ and other

processed foods high in fat, starches or

sugars – and consuming a ‘Western type’

diet (characterised by a high amount of

free sugars, meat and fat) – are causes

of weight gain, overweight and obesity by

increasing the risk of excess energy

intake relative to expenditure. Greater

body fatness is a cause of many cancers.

CancerNews: Africa

Do you know?

A researcher in

Tennessee (US) has

obtained a US patent on

four African medicinal

plants. The patent

makes sweeping claims

for preparations of the

plant extracts and

against “breast cancer,

leukemia, melanoma,

and myeloma” and

“viral infection,

diabetes, Parkinson's

disease, tuberculosis, or

fungal infections.”

The patent covers use of

Millettia ferruginea

alone or with one or

more of the other three

medicinal plants that are

claimed. All of the

plants grow in Ethiopia

and have medicinal uses

there and, in some cases,

other countries.

Page 5

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Our magazine suits adverts for things like pharmaceuticals, nutrients, cosmetics,

fashions, etc. Our audience is the general public, (especially women), health

institutions, research laboratories, gym and sports centers, cosmetics and beauty

centers, etc.

Advertising in our magazine is currently most ideal for businesses situated in

Nigeria and South Africa, targeting to impress their clientele and to attract more

prospective customers and collaborators.

Ingredients

1 medium banana (~7" long)

½ cup vanilla ice cream

6 oz milk (2%)

½ tsp cinnamon

Cooking Directions

Mix all ingredients in a blender and enjoy!

Adjust ingredients as desired.

Source: stanfordhealthcare.org/

Various banana extracts, fractions, and

phytoconstituents, including ferulic acid,

protocatechualdehyde, etc., have been

shown to exhibit cancer preventative

and anticancer activities in breast,

cervical, colorectal and others.

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